Advancing CRISPR-mediated Genome Editing Technology at UW–Madison to Model Human Disease

This project will establish advanced CRISPR technologies to enable genome editing in multiple mammalian species. Advancing the use of CRISPR-mediated genome editing technology at UW–Madison will accelerate the ability to generate genetically modified animal models of human disease.

Accurately modeling human disease states is critical for the development of new therapeutics. These efforts will promote groundbreaking research across the UW–Madison campus and fundamentally transform our ability to address critical biomedical issues across a wide spectrum of fields.

Principal Investigator

• Anjon Audhya
  Associate Professor of Biomolecular Chemistry
  

Co-Investigators

• Emery Bresnick
  Professor of Cell and Regenerative Biology
• Barak Blum
  Assistant Professor of Cell and Regenerative Biology
• Erik Dent
  Associate Professor of Neuroscience
• Emery Bresnick
  Professor of Cell and Regenerative Biology
• Thaddeus Golos
  Professor of Comparative Biosciences
• Meyer Jackson
  Professor of Neuroscience
• Sathish Kumar
  Associate Professor of Comparative Biosciences
• Matthew Merrins
  Assistant Professor of Medicine
• Darcie Moore
  Assistant Professor of Neuroscience
• David Pagliarini
  Associate Professor of Biochemistry and the Morgridge Institute for Research
• Robert Redfield
  Assistant Professor of Surgery
• Krishanu Saha
  Assistant Professor of Biomedical Engineering
• James Shull
  Professor of Oncology
• Beth Weaver
  Associate Professor of Cell and Regenerative Biology
• Jing Zhang
  Professor of Oncology
• Xinyu Zhao
  Professor of Neuroscience