Accelerating diabetes and metabolism research at UW–Madison
An obesity epidemic is sweeping across the United States including Wisconsin. Obesity is associated with an increased risk of diseases, including type 2 diabetes, cardiovascular disease, cancer and Alzheimer’s disease. Over 475,000 Wisconsin residents have diabetes, resulting in estimated healthcare costs of over $6 billion per year. An additional 1.4 million Wisconsinites over the age of 20 are estimated to have pre-diabetes. Diabetes adversely impacts under-represented minorities leading to higher rates and secondary complications.
This project establishes two new innovative research core facilities that will accelerate diabetes and metabolism research at UW–Madison by providing state-of-the-art experimental capacity to support a new Comprehensive Diabetes Center at UW–Madison. These new cores include a Mouse Phenotyping and Surgery Core (MPSC) and the Advanced Lipidomics Facility (ALF).
Mouse metabolic phenotyping is a crucial component of modern biomedical research and critical to experiments analyzing whole animal metabolism in mouse models of obesity, diabetes, aging, and many other diseases. The study of lipid metabolites will allow for the development of new diagnostic and therapeutic tools to combat diabetes and metabolic disease.
Dudley Lamming, assistant professor of endocrinology
Judith Simcox, assistant professor of biochemistry
Dawn Davis, associate professor of medicine and director of the UW–Madison Diabetes Research Center
Christopher Bradfield, professor of oncology and director of the UW Biotechnology Center
Alan Attie, professor of biochemistry
Rozalyn Anderson, associate professor medicine
Vincent Cryns, professor of medicine
Troy Hornberger, associate professor of comparative biosciences
Kristen Malecki, associate professor of population health sciences and director of the Survey of the Health of Wisconsin (SHOW)
David Pagliarini, associate professor of biochemistry and leader of the Morgridge Institute for Research Metabolism Theme
Federico Rey, associate professor of bacteriology