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University of Wisconsin–Madison

NIH High-End Instrumentation (HEI) Grant Program (S10) 2020

To:Chairs and Administrators, Departments in the Biological & Physical Sciences; Associate Deans for Research; College/School Research Administrators
From:Office of the Vice Chancellor for Research & Graduate Education
Date:February 20, 2020
Subject:NIH High-End Instrumentation (HEI) Grant Program (S10) 2020 PAR-20-114


Deadline for Notice of Intent:April 01, 2020

Project Description

The High-End Instrumentation (HEI) Grant Program encourages applications from groups of NIH-supported investigators to purchase or upgrade a single item of high-end, specialized, commercially available instruments or integrated systems.  The minimum award is $600,001. There is no maximum price limit for the instrument; however, the maximum award is $2,000,000.

Types of instruments supported include, but are not limited to: X-ray diffractometers, mass spectrometers, nuclear magnetic resonance (NMR) spectrometers, DNA and protein sequencers, biosensors, electron and light microscopes, cell sorters, high throughput robotic screening systems, and biomedical imagers.

Amount per Award: The minimum award is $600,001. There is no upper limit on the cost of the instrument, but the maximum award is $2,000,000.  S10 awards do not allow indirect costs.
Duration of Award: 1 Year – Earliest start date:  February 1, 2021
Number of Awards: ORIP intends to commit about $30 million in FY 2021 to fund an estimated 25 HEI awards


There is no limit on the number of applications an institution may submit, provided the applications are for different types of equipment. The NIH will not accept duplicate or highly overlapping applications under review at the same time.

Multiple applications from UW–Madison for similar instruments require official administrative assurance that such requests are a coordinated institutional effort and not unintended duplication. For this reason, Office of the Vice Chancellor for Research & Graduate Education review of the equipment requested is required.

This is not an internal competition.


Internal Competition Application Instructions

Applications for Internal Review

To submit your notice of intent, attach a single PDF to an email to:

Please include the following:

  • Cover Page including:  PI name, address, and department
  • Indication of  program intent:  HEI, SIG, or SIFAR
  • Name and description of the instrument
  • Statement of intended use
  • List of the potential users

Sponsor Deadlines

Applications are due to NIH by June 01, 2020.