Building a Translational Research Pipeline to Personalize Diabetes Prevention and Treatment
This project establishes the Diabetes Research Accelerator for Wisconsin (DRAW), a data registry and biobank of individuals with diabetes, as a next step toward delivering personalized diabetes care and facilitating interdisciplinary translational diabetes research at UW–Madison.
The long-term goal of this line of research is to improve the health for over 29 million people in the United States with type 1 or type 2 diabetes (T1D or T2D). Over 70% of diabetes patients do not achieve adequate blood sugar control, leading to significantly shortened healthy life and life-altering complications such as blindness, amputation, kidney failure, heart attack, and stroke. Although numerous treatment options and resources are available to help people manage their diabetes, often healthcare providers cannot specifically recommend which treatment is most likely to be effective for a given patient, resulting in a trial-and-error approach. Personalizing diabetes care could support successful early intervention and reduce the costs of failed treatments by addressing a host of biologic, environmental, and psychosocial risk factors. By building the DRAW resource, scientists at UW–Madison can more efficiently expand their ground-breaking work to human clinical populations.
Principal Investigator
- Elizabeth Cox
Associate Professor of Pediatrics
Co-Principal Investigators
- Dawn Davis
Associate Professor of Medicine - Michelle Kimple
Associate Professor of Medicine
Co-Investigators
- Jennifer Laffin
Associate Professor of Pediatrics – Genetics and Metabolism - Mari Palta
Professor of Population Health Sciences
- Ying Ge
Associate Professor of Chemistry
Collaborators
- Alan Attie
Professor of Biochemistry - Vincent Cryns
Professor of Medicine
- Feyza Engin
Assistant Professor of Medicine - Dudley Lamming
Assistant Professor of Medicine - Tamara LeCaire
Assistant Scientist in Population Health Sciences
- Kristina Matkowskyi
Assistant Professor of Pathology and Laboratory Medicine - Federico Rey
Assistant Professor of Bacteriology - Umberto Tachinardi
Associate Dean for Biomedical Informatics
- Chi-Liang Eric Yen
Associate Professor of Nutritional Sciences