Revitalization of Workhorse Fluorescence Microscopes for High-Speed and High-Resolution Imaging

Description:

This project provides essential upgrades to several microscope systems available in the UW–Madison Optical Imaging Core (UWOIC). The UWOIC enables access for campus investigators to high resolution imaging with state-of-the-art acquisition speed and limited phototoxicity to live specimens. For additional details on these upgrades as they become available, visit https://opticalcore.wisc.edu/.

The UWOIC offers imaging services on six microscopy systems. Imaging techniques available through the core include standard epifluorescence microscopy, super resolution microscopy, long-term live cell imaging, two-photon/intravital microscopy, spinning disk confocal imaging, lightsheet imaging, fluorescence spectral detection, photoactivation/uncaging, FRAP and calcium imaging. Offline computers are available for all users to conduct basic image analysis.

PRINCIPAL INVESTIGATOR:

Matthew Merrins, associate professor of medicine and scientific director of the UW–Madison Optical Imaging Core

CO-PRINCIPAL INVESTIGATOR:

Lance Rodenkirch, managing director of the UW–Madison Optical Imaging Core

CORE: 

UW–Madison Optical Imaging Core