Research Resources Reporter – Dec 4, 2018
CALLING ALL CORES
|PacBio Webinar on Single-Molecule Long Reads Dec 11, 2018
Learn about advances in SMRT sequencing from a vendor partner.Pacific Biosciences (PacBio) offers a webinar: A New Paradigm in DNA Sequencing: Highly Accurate Single-Molecule Long Reads on Tuesday, December 11, 2018, at 11:00 am (Central). PacBio summarizes the value of the seminar as:From those new to SMRT Sequencing to experienced users, this webinar will provide an update on recent performance improvements, scientific discoveries powered by PacBio and future applications to enable your research.What will you learn?
Registration is free.
|UWCCC Flow Cytometry Seminars Dec 13 and Dec 14, 2018
Seminars in data analysis and rigor and reproducibility in flow cytometryDecember 13, 10am in WIMR 7001B
Title: Basic Data Analysis, Gating, and Statistics in Flow Cytometry.
Description: An overview of data analysis considerations when working with flow data. We will talk about FCS files, visualizing data, gating, and statistics in flow cytometry. First in a series of 3 interactive seminars focusing on data analysis in flow cytometry presented by Alex HenkelDecember 14, 10 am in WIMR 7001A
Title: Rigor and Reproducibility in Flow Cytometry
Description: Dagna Sheerar will present various methodologies to improve rigor and reproducibility in flow cytometry experiments. Topics will include standardization techniques for ongoing studies, optimizing instrument sensitivity, optimizing panel sensitivity, standardizing data analysis, data management, and data annotation techniques specific to flow cytometry data sets.See the UWCCC Flow Lab for more resources and events.
|NSF Harnessing the Data Revolution Internal Applications due Dec 27, 2018
HDR: Data Science Corps 2019 limited competition for program deadline of Feb 4, 2019
NSF’s Harnessing the Data Revolution (HDR) Big Idea is a visionary, national-scale activity to enable new modes of data-driven discovery, allowing fundamentally new questions to be asked and answered in science and engineering frontiers, generating new knowledge and understanding, and accelerating discovery and innovation. The HDR vision is realized via a coordinated set of program solicitations resulting in an ecosystem of interrelated activities enabling (i) research in the foundations of data science; frameworks, algorithms, and systems for data science; and data-driven research in science and engineering; (ii) advanced cyberinfrastructure; and (iii) education and workforce development—all of which are designed to amplify the intrinsically multidisciplinary nature of the data science challenge. The HDR Big Idea will establish theoretical, technical, and ethical data science frameworks, and apply them to practical problems in science and engineering, and in society more generally.
|NCURA Webinar: Service Centers – The Not-So-Simple Basics
UW NetID access to session on federal costing standards and rate calculationsThe National Council of University Research Administrators advances expertise in research administration and offers high-quality educational opportunities. This webinar on service centers (fee-for-service research cores) is applicable to campus cores interested in understanding the federal guidance for setting rates.Webinar Description: [90 Minutes] This session will utilize an interactive, case-based approach to explore the basics of service centers. Using a fairly simple service center example, the session will address the calculation of rates based on federal costing standards, controls for compliant operation and considerations for successful service center financial management. Participants will have the ability to engage in a quiz-style format throughout the session and pose questions in a live, interactive forum.
Speakers: Sarah T. Axelrod- Assistant Vice President, Office for Sponsored Programs, Harvard University; Zach Belton- Director, HuronVisit External Resources at the bottom of the RSP Training page and click on NCURA Resources to log in with your netID.
|May Institute on Computation and Statistics Apr 2019
Northeastern University (Boston MA) hosts program for mass spec and proteomicsThe May Institute on computation and statistics for mass spectrometry and proteomics, taking place on April 29 – May 10, 2019 on campus of Northeastern University in Boston MA, is now accepting applications. Participants can select a subset of the following programs:
– Targeted proteomics with Skyline
– Proteomics and metabolomics with OpenMS
– [NEW THIS YEAR!] Imaging mass spectrometry with Cardinal
– Beginner’s statistics in R
– Advanced R
– Statistics for quantitative mass spectrometry
– Visualization of biomolecular data
– [NEW THIS YEAR!] Scientific writing
– Capstone – case studies in data-independent acquisition (DIA)Instructors are leading experts, who contributed numerous experimental and computational methods and software. The target audience are both beginners and experienced scientists, with both experimental and computational expertise.The application deadline is January 31, 2019. Tuition fee wavers and travel fellowships will be available for students and postdocs affiliated with academic institutions in the US. More information is at https://computationalproteomics.ccis.northeastern.edu/
Tissue Microarray comes to TRIP Lab
The TRIP Lab is offering tissue microarray (TMA) creation services with its brand new TMA Grand Master arrayer. This automated instrument can easily and quickly create TMA blocks with great precision and also extract paraffin embedded tissue samples to standard 0.2 ml PCR tubes to be used later in various molecular pathology applications. TMAs are a valuable, high-throughput method for diagnostic and research purposes. By being able to place hundreds of different samples into one paraffin block, TMAs bring major economies in time, quality and costs of tissue preparation, slide preparation and staining. For more information contact TRIP at email@example.com.
Small Animal Imaging and Radiotherapy Facility (SAIRF)
Small Animal Imaging Facility now manages three X-ray irradiators The Small Animal Imaging Facility has officially changed its name to Small Animal Imaging and Radiotherapy Facility (SAIRF) as it assumes management of three new X-ray producing irradiators (SARRP, XRAD320, and RS225) and for the facility’s capability to execute targeted radionuclide therapy (TRT) experiments. Please contact Justin Jeffery (firstname.lastname@example.org) for more information and all training inquiries for these new services.The SAIRF’s newest irradiator, the Small Animal Radiation Research Platform (SARRP) from Xstrahl, delivers targeted external beam radiation to pre-clinical animal models with great accuracy, conforming to a tissue of interest as is done in clinical radiotherapy. The system is equipped with a computed tomography (CT), allowing the user to contour a tissue of interest (ie. tumor) to evaluate the dose and to allow for animalized (akin to “personalized”) therapy.
|CORE SPOTLIGHT: Small Molecule Screening Facility (SMSF)
Find new drugs with high throughput screeningAre you interested in finding new drugs to cure cancer or solve the antibiotic crisis? Well, the Small Molecule Screening Facility (SMSF) can’t promise such broad success, but we can help you search through millions of compounds to find a few lead compounds that can be useful for nearly any research question you can ask. SMSF has expertise in high throughput screening, in computational modeling and docking for screening in silico, and in pharmacologically-informed sourcing of compounds for you from the millions of commercially available compounds. We also coordinate with the Medicinal Chemistry Center for synthesis of small molecules that can’t be purchased through your favorite vendor. For example, Tim Bugni and colleagues in Pharmacy recently worked with SMSF to screen a library of marine natural products for anti-cancer activity, starting with field-collected microbial samples and ending with filtered and fractionated growth medium of secondary metabolites used to screen cell cultures for anti-TGFb activity (an assay developed in-house, too!). All told, five lead compounds, biemamides A-E, were identified and their activity verified in an in vivo C. elegans assay. This publication is just one example of how SMSF staff can work with researchers to develop small molecule screening solutions to any number of biological questions. If your research could benefit from some new chemical tools, then contact SMSF today!